Brookline is an affluent town in Norfolk County, Massachusetts, in the United States, and part of the Boston metropolitan area. Brookline borders six of Boston's neighborhoods: Brighton, Allston, Fenway–Kenmore, Mission Hill, Jamaica Plain, and West Roxbury. The city of Newton lies to the west of Brookline.
Muddy Brookline was first settled in 1638 as a hamlet in Boston, known as Muddy River; it was incorporated as a separate town in 1705.
At the time of the 2020 United States Census, the population of the town was 63,191. It is the most populous municipality in Massachusetts to have a town (rather than city) form of government.
In its 2020 list of best places to live, Niche, the ranking and review website, placed Brookline as the best place to live in Massachusetts and the 10th in America.
Brookline was the birthplace and hometown of John F. Kennedy, 35th President of the United States.